Day 785
نویسندگان
چکیده
منابع مشابه
06. 785 D. Boixeda
Objetivo: la relación causal entre la rosácea y la infección por Helicobacter pylori es discutida. Se propuso valorar la evolución de los síntomas cutáneos de la rosácea tras la erradicación de la infección. Pacientes y métodos: se estudió prospectivamente a 44 pacientes diagnosticados de rosácea. Se determinó la infección por Helicobacter pylori y se administró terapia erradicadora a los pacie...
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Genome editing driven by zinc-finger nucleases (ZFNs) yields high gene-modification efficiencies (>10%) by introducing a recombinogenic double-strand break into the targeted gene. The cleavage event is induced using two custom-designed ZFNs that heterodimerize upon binding DNA to form a catalytically active nuclease complex. Using the current ZFN architecture, however, cleavage-competent homodi...
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Shenmai injection (SMI) is a popular herbal preparation that is widely used for the treatment of atherosclerotic coronary heart disease and viral myocarditis. In our previous study, SMI was shown to differentially affect CYP3A4-mediated 19-hydroxylation and 4-hydroxylation of midazolam (MDZ). The present study was conducted to identify the active components in SMI responsible for the differenti...
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A trinucleating framework was assembled by templation of a heptadentate ligand around yttrium and lanthanides. The generated complexes orient three sets of two or three N-donors each for binding additional metal centers. Addition of three equivalents of copper(I) leads to the formation of tricopper(I) species. Reactions with dioxygen at low temperatures generate species whose spectroscopic feat...
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Elevated levels of proinflammatory cytokines associated with infection and inflammation can modulate cytochrome P450 enzymes, leading to potential disease-drug interactions and altered small-molecule drug disposition. We established a human-derived hepatocyte-Kupffer cell (Hep:KC) coculture model to assess the indirect cytokine impact on hepatocytes through stimulation of KC-mediated cytokine r...
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ژورنال
عنوان ژورنال: Journal of Southeast Asian American Education and Advancement
سال: 2021
ISSN: 2153-8999
DOI: 10.7771/2153-8999.1227